KRAS G12C inhibitor 54

Names

[ CAS No. ]:
2765580-17-2

[ Name ]:
KRAS G12C inhibitor 54

Biological Activity

[Description]:

KRAS G12C inhibitor 54 (Compound 1) is a KRAS G12C inhibitor[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRAS(G12C)


[In Vitro]

KRAS G12C inhibitor 54 (Compound 1) shows antiproliferative activity with an IC50 of 4.85 nM against H358 cells[1].

[References]

[1]. Yuli XIE, et al. Quinazoline derivative, preparation method therefor and use thereof. WO2022063297A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C36H40F3N7O3S

[ Molecular Weight ]:
707.81

Related Compounds