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HPK1-IN-32

Names

[ CAS No. ]:
2766481-17-6

[ Name ]:
HPK1-IN-32

Biological Activity

[Description]:

HPK1-IN-32 is a potent and selective HPK1 inhibitor with an IC50 of 65 nM. HPK1-IN-32 can be used for the research of HPK1 related disorders or diseases[1].

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> MAP4K
Research Areas >> Cancer

[Target]

HPK1


[In Vitro]

HPK1-IN-32 (Example A34, 0-2 μM, 2 h) 抑制 Jurkat 细胞内 pSLP76 活性，IC50 为 65 nM[1]。

[References]

[1]. Sanjia XU, et al. 3-[(1h-pyrazol-4-yl)oxy]pyrazin-2-amine compounds as hpk1 inhibitor and use thereof. Patent. WO2022068848.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H37FN8O2

[ Molecular Weight ]:
536.64

Related Compounds