CYP3A4-IN-1

Names

[ CAS No. ]:
2771297-34-6

[ Name ]:
CYP3A4-IN-1

Biological Activity

[Description]:

CYP3A4-IN-1 (compound 5a) is a potent cytochrome P450 3A4 (CYP3A4) inhibitor with an IC50 value of 0.085 µM[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450

[Target]

CYP3A4:0.085 μM (IC50)


[References]

[1]. Samuels ER, et al. An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors of CYP3A4. Bioorg Med Chem. 2020 Mar 15;28(6):115349.

Chemical & Physical Properties

[ Molecular Formula ]:
C31H37N5O3S

[ Molecular Weight ]:
559.72

Related Compounds