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N-behenoyl-D-erythro-sphingosine

Names

[ CAS No. ]:
27888-44-4

[ Name ]:
N-behenoyl-D-erythro-sphingosine

[Synonym ]:
(2S,3R)-N-(docosanoate)-1,3-dihydroxy-2-amino-octadeca-4-(E)-ene
N-behenoyl-D-erythro-sphingosine

Biological Activity

[Description]:

C22-Ceramide (Cer d18:1/22:0) is an endogenous bioactive sphingolipid. C22-Ceramide reduces the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Stiban J, et al. Very long chain ceramides interfere with C16-ceramide-induced channel formation: A plausible mechanism for regulating the initiation of intrinsic apoptosis. Biochim Biophys Acta. 2015 Feb;1848(2):561-7.  

Chemical & Physical Properties

[ Molecular Formula ]:
C40H79NO3

[ Molecular Weight ]:
622.06

[ Exact Mass ]:
621.60600

[ PSA ]:
69.56000

[ LogP ]:
12.29450

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds