PBRM1-BD2-IN-4

Names

[ CAS No. ]:
2819989-60-9

[ Name ]:
PBRM1-BD2-IN-4

Biological Activity

[Description]:

PBRM1-BD2-IN-4 (compound 15) is a potent PBRM1 Bromodomain inhibitor with Kd values of 5.5 μM and 11.1 μM for PBRM1-BD2 and PBRM1-BD5, respectively, and an IC50 value of 0.2 μM for PBRM1-BD2. PBRM1-BD2-IN-4 can be used to research anticancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

[Target]

Kd: 5.5 μM (PBRM1-BD2), 11.1 μM (PBRM1-BD5)[1] IC50: 0.2 μM (PBRM1-BD2)[1]

Chemical & Physical Properties

[ Molecular Formula ]:
C15H13ClN2O

[ Molecular Weight ]:
272.73

Related Compounds