FGFR3-IN-4

Names

[ CAS No. ]:
2833706-13-9

[ Name ]:
FGFR3-IN-4

Biological Activity

[Description]:

FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR

[Target]

FGFR3:< 50 nM (IC50)


[In Vitro]

FGFR3 (example 297) 抑制 FGFR3 活性，IC50 值小于 50 nM[1]。

[References]

[1]. Abraham, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. WO2022187443.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H24ClN7O

[ Molecular Weight ]:
485.97

Related Compounds