N-(9-FLUORENYLMETHOXYCARBONYL)GLYCINE-

Names

[ Name ]:
N-(9-FLUORENYLMETHOXYCARBONYL)GLYCINE-

[Synonym ]:
Fmoc-Gly-OH-13C2,15N
MFCD01075396
Glycine-13C2,15N,N-Fmoc

Biological Activity

[Description]:

Fmoc-Gly-OH-13C2,15N is a 15N-labeled and 13C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-247.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-247.

Chemical & Physical Properties

[ Melting Point ]:
174-175ºC(lit.)

[ Molecular Formula ]:
C₁₅₁₃C₂H₁₅₁₅NO₄

[ Molecular Weight ]:
300.28

[ Exact Mass ]:
300.10400

[ PSA ]:
79.12000

[ LogP ]:
2.81410

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3