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Salicylic acid-D6

Names

[ CAS No. ]:
285979-87-5

[ Name ]:
Salicylic acid-D6

[Synonym ]:
Verrugon
Acid, Salicylic
Salicylic acid
Duoplant
Acid, 2-Hydroxybenzoic
Benzoic acid, o-hydroxy-
Acid, o-Hydroxybenzoic
2-hydroxy-benzoic acid
Hydroxybenzenecarboxylic acid
ortho Hydroxybenzoic Acid
2-hydroxybenzoic acid
Acid, ortho-Hydroxybenzoic
o-hydroxybenzoic acid
Duofilm
Benzoic acid, 2-hydroxy-
ORTHO-HYDROXYBENZOIC ACID
2-Hydroxybenzenecarboxylic acid
2 Hydroxybenzoic Acid
Keralyt

Biological Activity

[Description]:

Salicylic acid-D6 (2-Hydroxybenzoic acid-D6) is a deuterium labeled Salicylic acid. Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Autophagy >> Autophagy
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Immunology/Inflammation >> COX
Signaling Pathways >> Autophagy >> Mitophagy

[Target]

COX-2

Autophagy

Mitophagy

Apoptosis


[References]

[1]. Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
336.3±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C7D6O3

[ Molecular Weight ]:
138.121

[ Flash Point ]:
144.5±19.1 °C

[ Exact Mass ]:
138.031693

[ PSA ]:
37.30000

[ LogP ]:
2.06

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.616

Related Compounds