Sotolon

Names

[ Name ]:
Sotolon

[Synonym ]:
4,5-Dimethyl-3-Hydroxy-2(5H)-Furanone
3-Hydroxy-4,5-dimethyl-2(5H)-furanone
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
Sugar lactone
2(5H)-Furanone, 3-hydroxy-4,5-dimethyl-
3-hydroxy-4,5-dimethyl-5H-furan-2-one
Sotolone
UNII:T62RL2NEGW
Caramel furanone
2(5h)-FURANONE,3-HYDROXY-4,5-DIMETHYL
Fenugreek Lactone
MFCD00059957
Sotolon
4,5-dimethyl-isotetronic acid
3-Hydroxy-4,5-diméthyl-2(5H)-furanone
3-Hydroxy-4,5-dimethyl-2(5H)-furanon
3-Hydroxy-4,5-dimethylfuran-2(5H)-one
4,5-Dimethyl-3-hydroxy-2,5-dihydro-2-furanone
EINECS 249-136-4

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
312.0±42.0 °C at 760 mmHg

[ Melting Point ]:
26-29 °C(lit.)

[ Molecular Formula ]:
C₆H₈O₃

[ Molecular Weight ]:
128.126

[ Flash Point ]:
149.2±20.7 °C

[ Exact Mass ]:
128.047348

[ PSA ]:
46.53000

[ LogP ]:
-0.44

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.513

[ Storage condition ]:
Refrigerator (+4°C)

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/22:Harmful by inhalation and if swallowed .

[ Safety Phrases ]:
S36

[ RIDADR ]:
UN 3335

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Prooxidant action of furanone compounds: implication of reactive oxygen species in the metal-dependent strand breaks and the formation of 8-hydroxy-2'-deoxyguanosine in DNA.

Food Chem. Toxicol. 45(7) , 1258-62, (2007)

Prooxidant properties of furanone compounds including 2,5-furanone (furaneol, 4-hydroxy-2,5-dimethyl-furan-3-one), 4,5-furanone (4,5-dimethyl-3-hydroxy-2(5H)-furanone) (sotolone) and cyclotene (2-hydr...

Quantitative determination of sotolon, maltol and free furaneol in wine by solid-phase extraction and gas chromatography-ion-trap mass spectrometry.

J. Chromatogr. A. 1010(1) , 95-103, (2003)

A method for the analytical determination of sotolon [4,5-dimethyl-3-hydroxy-2(5H)-furanone], maltol [3-hydroxy-2-methyl-4H-pyran-4-one] and free furaneol [2,5-dimethyl-4-hydroxy-3(2H)-furanone] in wi...

3-Hydroxy-4,5-dimethyl-2(5H)-furanone (Sotolon) causing an off-flavor: elucidation of its formation pathways during storage of citrus soft drinks.

J. Agric. Food Chem. 47(8) , 3288-91, (1999)

Gas chromatography/olfactometry (GCO) and gas chromatography-mass spectrometry (HRGC-MS) revealed 3-hydroxy-4, 5-dimethyl-2(5H)-furanone (sotolon) to be responsible for the "burnt" and "spicy" off-fla...