D-Mannitol-2-13C

Names

[ CAS No. ]:
287100-69-0

[ Name ]:
D-Mannitol-2-13C

[Synonym ]:
D-Mannitol-2-13C

Biological Activity

[Description]:

D-Mannitol-2-13C is the 13C labeled D-Mannitol.

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Tan, K., et al., The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria. J Biol Chem, 2009. 284(52): p. 36670-9.;Nishiyama, A., et al., Mannitol lowers fat digestibility and body fat accumulation in both normal a

Chemical & Physical Properties

[ Melting Point ]:
167-170ºC(lit.)

[ Molecular Formula ]:
C₆H₁₄O₆

[ Molecular Weight ]:
183.16400

[ Exact Mass ]:
183.08200

[ PSA ]:
121.38000

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport