5-Bromonicotinamide

Names

[ Name ]:
5-Bromonicotinamide

[Synonym ]:
5-Brompyridin-3-carboxamid
5-Bromonicotinamide
bromonicotinamide
BRT
5-Bromopyridine-3-carboxamide
3-Pyridinecarboxamide, 5-bromo-
Nicotinamide,5-bromo
3-bromonicotinamide
5-Bromo-nicotinamide
5-Bromo-3-pyridinecarboxamide
MFCD00173919
3-Bromo-5-carbamoylpyridine
EINECS 244-065-5
5-bromo-3-pyridine carboxamide

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
315.5±27.0 °C at 760 mmHg

[ Melting Point ]:
219-223 °C

[ Molecular Formula ]:
C₆H₅BrN₂O

[ Molecular Weight ]:
201.021

[ Flash Point ]:
144.6±23.7 °C

[ Exact Mass ]:
199.958511

[ PSA ]:
55.98000

[ LogP ]:
1.05

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.614

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QS4170000

CHEMICAL NAME :: Nicotinamide, 5-bromo-

CAS REGISTRY NUMBER :: 28733-43-9

BEILSTEIN REFERENCE NO. :: 0115921

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H5-Br-N2-O

MOLECULAR WEIGHT :: 201.04

WISWESSER LINE NOTATION :: T6NJ CE EVZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 20,29,1986

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
QS4170000

[ HS Code ]:
2933399090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Simultaneous determination of the bilirubin oxidation end products Z-BOX A and Z-BOX B in human serum using liquid chromatography coupled to tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 974 , 83-9, (2014)

Bilirubin oxidation end products (BOXes) appear upon endogenous heme degradation and can be found in the cerebrospinal fluid after hemorrhagic stroke. BOXes are assumed to contribute to delayed cerebr...