R(+)-6-CHLORO-7,8-DIHYDROXY-3-METHYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

Names

[ Name ]:
R(+)-6-CHLORO-7,8-DIHYDROXY-3-METHYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

[Synonym ]:
(R)-SKF-82957 hydrobromide
1H-3-Benzazepine-7,8-diol,6-chloro-2,3,4,5-tetrahydro-3-methyl-1-phenyl hydrobromide hydrobromide

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₉BrClNO₂

[ Molecular Weight ]:
384.69500

[ Exact Mass ]:
383.02900

[ PSA ]:
52.49000

[ LogP ]:
4.62410

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines.

J. Med. Chem. 25 , 352, (1982)

6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines were synthesized and evaluated as agonists of central and peripheral dopamine receptors. These benzazepines were prepared by cycliz...

Dopamine receptor agonists: selectivity and dopamine D1 receptor efficacy.

Eur. J. Pharmacol. 188 , 335-347, (1990)

Dopamine receptor selectivity was investigated for a number of dopamine receptor agonists. In vitro, the benzazepine derivatives, e.g., SKF 38393 and SKF 75670 as well as the isoquinoline derivatives,...