3-(carbamoylamino)-2-methyl-propanoic acid
Names
[ CAS No. ]:
2905-86-4
[ Name ]:
3-(carbamoylamino)-2-methyl-propanoic acid
[Synonym ]:
3-carbamoylamino-2-methylpropanoic acid
3-Ureido-isobuttersaeure
3-ureido-2-methyl-propanoic acid
3-Ureidoisobutyrate
3-(carbamoylamino)-2-methylpropanoic acid
DL-3-Ureidoisobutyric acid
Chemical & Physical Properties
[ Density]:
1.263g/cm3
[ Boiling Point ]:
317.5ºC at 760mmHg
[ Molecular Formula ]:
C5H10N2O3
[ Molecular Weight ]:
146.14400
[ Flash Point ]:
145.8ºC
[ Exact Mass ]:
146.06900
[ PSA ]:
93.41000
[ LogP ]:
0.28010
[ Vapour Pressure ]:
8.12E-05mmHg at 25°C
[ Index of Refraction ]:
1.497
MSDS
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H318
[ Precautionary Statements ]:
P280-P305 + P351 + P338 + P310
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2924199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Hum. Mol. Genet. 13(22) , 2793-801, (2004)
beta-Ureidopropionase deficiency is an inborn error of the pyrimidine degradation pathway, affecting the cleavage of N-carbamyl-beta-alanine and N-carbamyl-beta-aminoisobutyric acid. In this study, we...
Sensitive method for the quantification of urinary pyrimidine metabolites in healthy adults by gas chromatography-tandem mass spectrometry.J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 791(1-2) , 371-80, (2003)
Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil. To assess whether urinary levels of pyrimidines and their m...
Screening and diagnosis of beta-ureidopropionase deficiency by gas chromatographic/mass spectrometric analysis of urine.J. Mass Spectrom. 37(9) , 954-62, (2002)
Dihydropyrimidine dehydrogenase (DHPDase), dihydropyrimidinase (DHPase) and beta-ureidopropionase (betaUPase) are the enzymes that catalyze the first, second, and third steps of the degradation of pyr...