terofenamate
Names
[ CAS No. ]:
29098-15-5
[ Name ]:
terofenamate
[Synonym ]:
Terofenamato [INN-Spanish]
Etofen
Etoclofene
EINECS 249-434-4
Terofenamate
N-(2,6-Dichloro-m-tolyl)anthranilic acid ethoxymethyl ester
M-(2,6-Dichloro-m-tolyl)anthranilic acid ethoxymethyl ester
Ethoxymethyl N-(2,6-dichloro-m-tolyl)anthranilate
Terofenamatum [INN-Latin]
Chemical & Physical Properties
[ Density]:
1.297g/cm3
[ Boiling Point ]:
439ºC at 760 mmHg
[ Molecular Formula ]:
C17H17Cl2NO3
[ Molecular Weight ]:
354.22800
[ Flash Point ]:
219.3ºC
[ Exact Mass ]:
353.05900
[ PSA ]:
47.56000
[ LogP ]:
5.26920
[ Vapour Pressure ]:
6.6E-08mmHg at 25°C
[ Index of Refraction ]:
1.597
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CB2975100
- CHEMICAL NAME :
- Anthranilic acid, N-(2,6-dichloro-m-tolyl)-, ethoxymethyl ester
- CAS REGISTRY NUMBER :
- 29098-15-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C17-H17-Cl2-N-O3
- MOLECULAR WEIGHT :
- 354.25
- WISWESSER LINE NOTATION :
- GR CG D1 BMR BVO1O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 307 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cough
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,41,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 274 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cough
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,41,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 918 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,41,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,41,1976 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6240 mg/kg/26W-I
- TOXIC EFFECTS :
- Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in leukocyte (WBC) count Related to Chronic Data - death
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,41,1976
Safety Information
[ HS Code ]:
2922509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%