Adenine hydrochloride

Names

[ Name ]:
Adenine hydrochloride

[Synonym ]:
6-Aminopurine hydrochloride hydrate
7H-Purin-6-amine hydrochloride
7H-Purin-6-amine hydrochloride (1:1)
MFCD00075782
Adenine monohydrochloride
7H-Purin-6-amine, hydrochloride (1:1)
Adenine hydrochloride
6-Aminopurine Hydrochloride Hemihydrate
EINECS 220-867-0

Biological Activity

[Description]:

Adenine hydrochloride (6-Aminopurine hydrochloride) is a purine derivative with a variety of roles in biochemistry, including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), and protein synthesis, as a chemical component of DNA and RNA[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[Target]

Target: Human Endogenous Metabolite

[References]

[1]. Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31.

[2]. ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27.

Chemical & Physical Properties

[ Boiling Point ]:
553.5ºC at 760 mmHg

[ Melting Point ]:
~285 °C (dec.)

[ Molecular Formula ]:
C₅H₆ClN₅

[ Molecular Weight ]:
171.588

[ Flash Point ]:
322.7ºC

[ Exact Mass ]:
171.031174

[ PSA ]:
80.48000

[ LogP ]:
1.31830

[ Water Solubility ]:
H2O: 50 mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
26-36

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%