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CK2/PIM1-IN-1

Names

[ CAS No. ]:
292640-28-9

[ Name ]:
CK2/PIM1-IN-1

Biological Activity

[Description]:

CK2/PIM1-IN-1 is an inhibitor of CK2 and PIM1, with IC50s of 3.787 μM and 4.327 μM for CK2 and PIM1, respectively. CK2/PIM1-IN-1 is developed for the research of proliferative disorders such as cancer, as well as other kinase-associated conditions including inflammation, pain, vascular disorders, pathogenic infections and certain immunological disorders[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> JAK/STAT Signaling >> Pim
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase
Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase

[Target]

CK2:3.787 μM (IC50)

PIM1:4.327 μM (IC50)


[In Vitro]

CK2/PIM1-IN-1 a PIM kinases and CK2 inhibitor extracted from patent WO2010148351A1, Compound Example 64[1].

[References]

[1]. Mustapha Haddach, et al. Rhodanines and related heterocycles as kinase inhibitors. WO2010148351A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H9NO4S2

[ Molecular Weight ]:
331.37

Related Compounds