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13-Oxo-9E,11E-octadecadienoic acid

Names

[ CAS No. ]:
29623-29-8

[ Name ]:
13-Oxo-9E,11E-octadecadienoic acid

[Synonym ]:
13-oxo-9Z,11E/Z-octadecadienoic acid
13-Oxo-9,11-octadecadiensaeure
13-Oxo-9E,11E-octadecadienoicacid
13-Oxo-9E,11E-octadecadienoic acid

Biological Activity

[Description]:

13-Oxo-9E,11E-octadecadienoic acid, an isomer of 9-oxo-ODA, is a potent PPARα activator derived from tomato juice. 13-Oxo-9E,11E-octadecadienoic acid decreases plasma and hepatic triglyceride in obese diabetic mice[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

[Target]

PPARα


[In Vivo]

13-Oxo-9E,11E-octadecadienoic acid (feed; 0.02% and 0.05%; for 4 weeks) improves dyslipidemia and lowering TG content in the liver and skeletal muscle of HFD-fed KK-Ay mice[1]. Animal Model: Male KK-Ay mice with 4-week-old[1] Dosage: 0.02% and 0.05% Administration: Feed; for 4 weeks Result: Improved dyslipidemia and lowering TG content in the liver and skeletal muscle of HFD-fed KK-Ay mice.

[References]

[1]. Kim YI, et al. Potent PPARα activator derived from tomato juice, 13-oxo-9,11-octadecadienoic acid, decreasesplasma and hepatic triglyceride in obese diabetic mice. PLoS One. 2012;7(2):e31317.

Chemical & Physical Properties

[ Density]:
0.966±0.06 g/cm3(Predicted)

[ Boiling Point ]:
425.5±18.0 °C(Predicted)

[ Molecular Formula ]:
C18H30O3

[ Molecular Weight ]:
294.42900

[ Exact Mass ]:
294.21900

[ PSA ]:
54.37000

[ LogP ]:
5.06350

Related Compounds