MEK Inhibitor I

Names

[ Name ]:
MEK Inhibitor I

[Synonym ]:
MEK Inhibitor I
Benzeneacetonitrile, α-[amino[(2-aminophenyl)thio]methylene]-3-(hydroxy-4-pyridinylmethyl)-, (αZ)-
(2Z)-3-Amino-3-[(2-aminophenyl)sulfanyl]-2-{3-[hydroxy(4-pyridinyl)methyl]phenyl}acrylonitrile
(2Z)-3-amino-3-[(2-aminophenyl)sulfanyl]-2-{3-[hydroxy(pyridin-4-yl)methyl]phenyl}prop-2-enenitrile

Biological Activity

[Description]:

MEK-IN-4 is a MEK inhibitor. MEK-IN-4 can be used for the research of inflammatory disorders and cancers[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> MAPK/ERK Pathway >> MEK

Research Areas >> Inflammation/Immunology

[References]

[1]. Frank W. Hobbs, et al. Amino-thio-acrylonitriles as mek inhibitors. Patent. WO2000056706A1.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
671.9±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₁₈N₄OS

[ Molecular Weight ]:
374.459

[ Flash Point ]:
360.2±31.5 °C

[ Exact Mass ]:
374.120117

[ LogP ]:
-0.11

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.727

MEK Inhibitor I

Names

Biological Activity

Chemical & Physical Properties

Related Compounds