3-Morpholinobenzanthrone

Names

[ Name ]:
3-Morpholinobenzanthrone

[Synonym ]:
3-Morpholino-7H-benz[de]anthracen-7-one
3-morpholin-4-ylbenzo[b]phenalen-7-one

Biological Activity

[Description]:

3-Morpholinobenzanthrone is a fluorescent membrane probe, possessing higher dipole moment values in the excited-state than in the ground-state[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. B.Siddlingeshwar, et al. Photophysical characteristics of three novel benzanthrone derivatives: Experimental and theoretical estimation of dipole moments. J Quant Spectrosc Radiat Transf. 2011 Feb., 112 (3), 448-456.

Chemical & Physical Properties

[ Density]:
1.301g/cm3

[ Boiling Point ]:
556.5ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₁₇NO₂

[ Molecular Weight ]:
315.36500

[ Flash Point ]:
290.4ºC

[ Exact Mass ]:
315.12600

[ PSA ]:
29.54000

[ LogP ]:
3.95280

[ Index of Refraction ]:
1.699

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

HIV-1 fusion inhibitor peptides enfuvirtide and T-1249 interact with erythrocyte and lymphocyte membranes.

PLoS ONE 5 , e9830, (2010)

Enfuvirtide and T-1249 are two HIV-1 fusion inhibitor peptides that bind to gp41 and prevent its fusogenic conformation, inhibiting viral entry into host cells. Previous studies established the relati...

Evaluation of a fluorescent derivative of AMD3100 and its interaction with the CXCR4 chemokine receptor.

ChemBioChem. 12 , 2692-2698, (2011)

AMD3100 is a potent and selective antagonist of the CXCR4 receptor; it has been shown to block the route of entry of HIV into host T-cells. This compound and its analogues have since been found to act...

Suitability of various membrane lipophilic probes for the detection of trogocytosis by flow cytometry.

Cytometry 75 , 380-389, (2009)

Trogocytosis is a recently discovered phenomenon whereby lymphocytes capture fragments of the plasma membrane from antigen presenting cells (APCs). Using APCs labeled with widely used fluorescent lipo...