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S 24795

Names

[ CAS No. ]:
304679-75-2

[ Name ]:
S 24795

[Synonym ]:
2-[2-(4-Bromophenyl)-2-oxoethyl]-1-methyl pyridinium iodide

Biological Activity

[Description]:

S 24795 is a partial agonist of α7 nAChR and improves mnemonic function in aged mice for the treatment of aging-related memory disturbances[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR
Signaling Pathways >> Neuronal Signaling >> nAChR
Research Areas >> Neurological Disease

[References]

[1]. Lagostena L, et al. The partial alpha7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus. Neuropharmacology. 2008 Mar;54(4):676-85.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H13BrINO

[ Molecular Weight ]:
418.06800

[ Exact Mass ]:
416.92300

[ PSA ]:
20.95000

[ Appearance of Characters ]:
white to light brown

[ Storage condition ]:
Store at +4°C

[ Water Solubility ]:
H2O: soluble1mg/mL, clear (warmed)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

Related Compounds