<Suppliers Price>

sodiumiodoacetate

Names

[ CAS No. ]:
305-53-3

[ Name ]:
sodiumiodoacetate

[Synonym ]:
lithium iodoacetate
sodiumiodoacetate
Sodium monoiodoacetate
EINECS 206-165-7
Sodium iodacetate
USAF EK-6279
2-iodoacetic acid sodium salt
Iodoacetic acid sodium salt
Sodium iodoacetate
Iodoacetic acid,sodium salt
Acetic acid, 2-iodo-, sodium salt (1:1)
MFCD00002686
Iodoacetate,sodium salt

Chemical & Physical Properties

[ Boiling Point ]:
262.1ºC at 760mmHg

[ Melting Point ]:
208 °C (dec.)(lit.)

[ Molecular Formula ]:
C2H2INaO2

[ Molecular Weight ]:
207.930

[ Flash Point ]:
112.3ºC

[ Exact Mass ]:
207.899704

[ PSA ]:
40.13000

[ Storage condition ]:
−20°C

[ Water Solubility ]:
methanol: 0.1 M at 20 °C, clear, colorless

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AI3675000
CHEMICAL NAME :
Acetic acid, iodo-, sodium salt
CAS REGISTRY NUMBER :
305-53-3
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C2-H2-I-O2.Na
MOLECULAR WEIGHT :
207.93
WISWESSER LINE NOTATION :
OV1I &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
83 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
500 mg/kg
SEX/DURATION :
female 8-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - live birth index (measured after birth) Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - rat Liver
DOSE/DURATION :
10 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 368,59,1996

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R25;R36/37/38

[ Safety Phrases ]:
S26-S39-S45

[ RIDADR ]:
UN 2811 6.1/PG 1

[ WGK Germany ]:
3

[ RTECS ]:
AI3675000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2915900090

Precursor & DownStream

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics.

MAbs 7 , 881-90, (2015)

Regulatory agencies have recently recommended a Quality by Design (QbD) approach for the manufacturing of therapeutic molecules. A QbD strategy requires deep understanding at the molecular level of th...

Thrombin-facilitated efflux of D-[3H]-aspartate from cultured astrocytes and neurons under hyponatremia and chemical ischemia.

Neurochem. Res. 39(7) , 1219-31, (2014)

Thrombin effect increasing swelling-induced glutamate efflux was examined in cultured cortical astrocytes, cerebellar granule neurons (CGN), hippocampal and cortical neurons. Hypotonic glutamate efflu...

Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response.

PLoS ONE 10(4) , e0123721, (2015)

High-grade gliomas, glioblastomas (GB), are refractory to conventional treatment combining surgery, chemotherapy, mainly temozolomide, and radiotherapy. This highlights an urgent need to develop novel...


More Articles


Related Compounds