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NNC 0640

Names

[ CAS No. ]:
307986-98-7

[ Name ]:
NNC 0640

Biological Activity

[Description]:

NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM[1].

[Related Catalog]:

Research Areas >> Metabolic Disease
Signaling Pathways >> GPCR/G Protein >> Glucagon Receptor

[Target]

Human Glucagon Receptor [1]


[References]

[1]. Zhang H, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. 2017 Jun 8;546(7657):259-264.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H31N7O4S

[ Molecular Weight ]:
573.67

[ Storage condition ]:
-20°C

Related Compounds