N,N-Dimethyl-2′-O-methyladenosine

Names

[ CAS No. ]:
30891-53-3

[ Name ]:
N,N-Dimethyl-2′-O-methyladenosine

[Synonym ]:
Adenosine,N,N-dimethyl-2'-O-methyl

Biological Activity

[Description]:

N,N-Dimethyl-2′-O-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C13H19N5O4

[ Molecular Weight ]:
309.32

[ Exact Mass ]:
309.14400

[ PSA ]:
105.76000

Related Compounds