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[Glu27]-PKC (19-36)

Names

[ CAS No. ]:
309247-49-2

[ Name ]:
[Glu27]-PKC (19-36)

[Synonym ]:
L-Asparagine, L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysylglycyl-L-alanyl-L-leucyl-L-α-glutamyl-L-glutaminyl-L-lysyl-L-asparaginyl-L-valyl-L-histidyl-L-α-glutamyl-L-valyl-L-lysyl-
L-Arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysylglycyl-L-alanyl-L-leucyl-L-α-glutamyl-L-glutaminyl-L-lysyl-L-asparaginyl-L-valyl-L-histidyl-L-α-glutamyl-L-valyl-L-lysyl-L-asparagine

Biological Activity

[Description]:

[Glu27]-PKC (19-36) is an inactive control for protein kinase C (PKC) (19-36). PKC (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C, it may be responsible for maintaining the enzyme in the inactive form in the absence of allosteric activators such as phospholipids[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. House C, Kemp BE. Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. Science. 1987 Dec 18;238(4834):1726-8.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C92H154N32O26

[ Molecular Weight ]:
2124.406

[ Exact Mass ]:
2123.171143

[ LogP ]:
-7.78

[ Index of Refraction ]:
1.660

Related Compounds