N-ACETYL-ALPHA-D-GLUCOSAMINE 6-PHOSPHATE DISODIUM SALT

Names

[ Name ]:
N-ACETYL-ALPHA-D-GLUCOSAMINE 6-PHOSPHATE DISODIUM SALT

[Synonym ]:
N-Acetyl-|A-D-glucosamine 1-phosphate disodium salt

Biological Activity

[Description]:

N-acetyl-α-d-glucosamine 1-phosphate disodium (GlcNAc-1-P), an anomeric sugar phosphate, is a key intermediate in the biosynthesis of N-linked glycoproteins. N-acetyl-α-d-glucosamine 1-phosphate disodium is a metabolic precursor of the bacterial cell-wall components teichoic acid and mureine[1].

[Related Catalog]:

Research Areas >> Others

[Target]

Microbial Metabolite

[References]

[1]. Olivier Gaurat, et al. A concise synthesis of C-glycosyl phosphate and phosphonate analogues of N-acetyl-α-d-glucosamine 1-phosphate. Tetrahedron Letters. 19 February 2000,41(18):1187-1189.

Chemical & Physical Properties

[ Molecular Formula ]:
C₈H₁₅NNaO₉P

[ Molecular Weight ]:
323.17000

[ Exact Mass ]:
323.03800

[ PSA ]:
178.42000

[ Storage condition ]:
20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

LmbE proteins from Bacillus cereus are de-N-acetylases with broad substrate specificity and are highly similar to proteins in Bacillus anthracis.

FEBS J. 277 , 2740-2753, (2010)

The genomes of Bacillus cereus and its closest relative Bacillus anthracis each contain two LmbE protein family homologs: BC1534 (BA1557) and BC3461 (BA3524). Only a few members of this family have be...