MMG 11

Names

[ Name ]:
MMG 11

Biological Activity

[Description]:

MMG-11 is a potent and selective human TLR2 antagonist. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with an IC50 of 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)

Research Areas >> Inflammation/Immunology

[Target]

TLR2

[References]

[1]. Grabowski M, et al. Identification of a pyrogallol derivative as a potent and selective human TLR2 antagonist by structure-based virtual screening. Biochem Pharmacol. 2018 Aug;154:148-160.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₄O₇

[ Molecular Weight ]:
306.27

[ Storage condition ]:
-20°C

MMG 11

Names

Biological Activity

Chemical & Physical Properties

Related Compounds