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LY-517717

Names

[ CAS No. ]:
313489-71-3

[ Name ]:
LY-517717

Biological Activity

[Description]:

LY-517717 is a potent and orally active FXa inhibitor. LY-517717 shows antithrombotic and anticoagulant activity. LY-517717 has the potential for the research of venous thromboembolism after hip or knee replacement[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> Factor Xa

[References]

[1]. Agnelli G, et al. A phase II study of the oral factor Xa inhibitor LY517717 for the prevention of venous thromboembolism after hip or knee replacement. J Thromb Haemost. 2007 Apr;5(4):746-53.  

Chemical & Physical Properties

[ Molecular Formula ]:
C27H33N5O2

[ Molecular Weight ]:
459.58300

[ Exact Mass ]:
459.26300

[ PSA ]:
75.17000

[ LogP ]:
3.26590

Related Compounds