A 922500
Names
[ CAS No. ]:
314-19-2
[ Name ]:
A 922500
[Synonym ]:
6aβ-Noraporphine-10,11-diol, 6-methyl-, hydrochloride
apomorphine HCl
6aβ-Aporphine-10,11-diol, hydrochloride (8CI)
apomorphinechloride
EINECS 206-243-0
4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, (6aR)-, hydrochloride (1:1)
(6aR)-6-méthyl-5,6,6a,7-tétrahydro-4H-dibenzo[de,g]quinoléine-10,11-diol chlorhydrate
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride
4H-dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, (6aR)-, hydrochloride
Apomorphine hydrochoride
(-)-apomorphine hydrochloride
(6aR)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]chinolin-10,11-diolhydrochlorid
(6aR)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride (1:1)
6aβ-Aporphine-10,11-diol, hydrochloride
apomorphiniumchloride
6-Methyl-6ab-noraporphine-10,11-diol Hydrochloride
6ab-Aporphine-10,11-diol Hydrochloride
APOMORPHINE HYDROCHLORIDE
UPRIMA
Chemical & Physical Properties
[ Boiling Point ]:
473.4ºC at 760mmHg
[ Melting Point ]:
195ºC (decomposes)
[ Molecular Formula ]:
C17H18ClNO2
[ Molecular Weight ]:
303.783
[ Flash Point ]:
268.8ºC
[ Exact Mass ]:
303.102600
[ PSA ]:
43.70000
[ LogP ]:
3.58980
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HQ1750000
- CHEMICAL NAME :
- 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, (R)-
- CAS REGISTRY NUMBER :
- 314-19-2
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C17-H17-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 303.81
- WISWESSER LINE NOTATION :
- T C6666 1A Q KN&TT&J DQ EQ K1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 145 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 38 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraarterial
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 20 ug/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 137,17,1984
Safety Information
[ RIDADR ]:
UN 3249
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)