8-Azidoadenosine 3':5'-cyclic monophosphate

Names

[ CAS No. ]:
31966-52-6

[ Name ]:
8-Azidoadenosine 3':5'-cyclic monophosphate

[Synonym ]:
8-AZIDOADENOSINE 3':5'-CYCLICMONOPHOSPHA TE FREE AC
8-Azidoadenosine 3',5'-cyclic monophosphosphate free acid
8-AZIDOADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
8-N3-CAMP SODIUM SALT
8-AZIDOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT

Biological Activity

[Description]:

8-Azido-cAMP is a fluorescent cAMP analog, acting as the model target of detecting cAMP[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Ito K, et al. Direct light-up of cAMP derivatives in living cells by click reactions. Molecules. 2013 Oct 17;18(10):12909-15

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₁N₈O₆P

[ Molecular Weight ]:
370.21800

[ Exact Mass ]:
370.05400

[ PSA ]:
214.40000

[ LogP ]:
0.15836

Safety Information

[ WGK Germany ]:
3

Articles

The covalent labeling of proteins by 17 beta-estradiol, retinoic acid, and progesterone in the human breast cancer cell lines MCF-7 and MCF-7/AdrR.

J. Steroid Biochem. Mol. Biol. 43(6) , 489-97, (1992)

In this study we analyzed the covalent binding to proteins of 17 beta-estradiol (E2), retinoic acid (RA), and progesterone in MCF-7 and MCF-7/AdrR cells. MCF-7 cells have receptors for E2 and progeste...

A highly decreased binding of cyclic adenosine monophosphate to protein kinase A in erythrocyte membranes is specific for active psoriasis.

J. Invest. Dermatol. 119(1) , 160-5, (2002)

A cyclic adenosine monophosphate binding abnormality in psoriatic erythrocytes that could be corrected by retinoid treatment has been reported. It was tested whether this binding abnormality is specif...

Lipolytic membrane release of two phosphatidylinositol-anchored cAMP receptor proteins in yeast alters their ligand-binding parameters.

Arch. Biochem. Biophys. 308(2) , 504-14, (1994)

Two new cAMP-binding proteins have been discovered recently in Saccharomyces cerevisiae. They are genetically distinct from the regulatory subunit of cytoplasmic cAMP-dependent protein kinase A and ar...