SKF-34288 hydrochloride
Names
[ CAS No. ]:
320386-54-7
[ Name ]:
SKF-34288 hydrochloride
[Synonym ]:
3-Mercapto-2-pyridinecarboxylic Acid Hydrochloride
3-Mercaptopicolinic Acid Hydrochloride
Biological Activity
[Description]:
SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is a phosphoenolpyruvate carboxykinase (PEPCK) inhibitor.SKF-34288 hydrochloride is a potent hypoglycemic agent via inhibition of glucose synthesis through the specific inhibition of PEPCK in the gluconeogenesis pathway[1]. SKF-34288 hydrochloride inhibits Asn metabolism and results in an increase in amino acids and amides[2].
[Related Catalog]:
[Target]
IC50: PEPCK[1]
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C6H6ClNO2S
[ Molecular Weight ]:
191.63500
[ Exact Mass ]:
190.98100
[ PSA ]:
88.99000
[ LogP ]:
1.87050