3-chloro-N-(pyridin-3-ylmethyl)-1-benzothiophene-2-carboxamide

Names

[ Name ]:
3-chloro-N-(pyridin-3-ylmethyl)-1-benzothiophene-2-carboxamide

[Synonym ]:
MFCD00227426
Benzo[b]thiophene-2-carboxamide, 3-chloro-N-(3-pyridinylmethyl)-
3-Chloro-N-(3-pyridinylmethyl)-1-benzothiophene-2-carboxamide

Biological Activity

[Description]:

GluR6 antagonist-1 is a benzothiophene derivative, acting as a GluR6 antagonist. GluR6 antagonist-1 can be used for researching acute and chronic neurological disorders[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[Target]

GluR6[1]

[References]

[1]. BAKER STEPHEN RICHARD, et al. BENZOTHIOPHENE DERIVATIVES. WO2001007431 A2 (example 20)

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
543.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₁ClN₂OS

[ Molecular Weight ]:
302.779

[ Flash Point ]:
282.5±30.1 °C

[ Exact Mass ]:
302.028076

[ LogP ]:
3.71

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.688