NAAA-IN-2

Names

[ CAS No. ]:
325775-42-6

[ Name ]:
NAAA-IN-2

Biological Activity

[Description]:

NAAA-IN-2 (Compound 9) is a potent and selective inhibitor of NAAA with an IC50 of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-2 has the potential for the research of inflammation and pain[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Malamas MS, et al. Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors. Bioorg Med Chem. 2020 Jan 1;28(1):115195.

Chemical & Physical Properties

[ Molecular Formula ]:
C11H13N3O2S

[ Molecular Weight ]:
251.30

Related Compounds