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1,2-dipalmitoyl-d62-sn-glycero-3-[phospho-rac-(1-glycerol)] (sodium salt)

Names

[ CAS No. ]:
326495-46-9

[ Name ]:
1,2-dipalmitoyl-d62-sn-glycero-3-[phospho-rac-(1-glycerol)] (sodium salt)

[Synonym ]:
Sodium (2R)-2,3-bis[(H)hexadecanoyloxy]propyl 2,3-dihydroxypropyl phosphate
Hexadecanoic-d acid, (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, sodium salt (1:1)

Biological Activity

[Description]:

DPPG-d62 (sodium) is deuterium labeled DPPG. DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, l

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].

[References]

[1]. Ege C, Lee KY. Insertion of Alzheimer's A beta 40 peptide into lipid monolayers. Biophys J. 2004 Sep;87(3):1732-40.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Chemical & Physical Properties

[ Molecular Formula ]:
C38H12D62NaO10P

[ Molecular Weight ]:
807.334

[ Exact Mass ]:
806.880859

[ Storage condition ]:
-20°C


Related Compounds