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7-O-Methylaloeresin A

Names

[ CAS No. ]:
329361-25-3

[ Name ]:
7-O-Methylaloeresin A

[Synonym ]:
(1S)-1,5-Anhydro-2-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-1-[7-methoxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-chromen-8-yl]-D-glucitol
D-Glucitol, 1,5-anhydro-2-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-1-C-[7-methoxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-1-benzopyran-8-yl]-, (1S)-
(1S)-1,5-Anhydro-2-O-[(2E)-3-(4-hydroxyphenyl)-2-propenoyl]-1-[7-methoxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-chromen-8-yl]-D-glucitol
(1S)-1,5-anhydro-2-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-1-[7-methoxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-chromen-8-yl]glucitol
D-glucitol, 1,5-anhydro-2-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-1-C-[7-methoxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-1-benzopyran-8-yl]-, (1S)-
O-Methylaloeresin A, 7-

Biological Activity

[Description]:

7-O-Methylaloeresin A is 5-methylchromone glycoside isolated from Commiphora socotrana (Burseraceae)[1]. 7-O-Methylaloeresin A exhibits good activity against multiple drug resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mM, respectively[2].7-O-Methylaloeresin A has antioxidant activities, gives IC50 values of 0.026  mM and 0.021  mM for DPPH and 2-deoxyribose degradation assay, respectively[2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Blitzke T, et al. 7-O-methylaloeresin A--a new chromone glycoside from Commiphora socotrana. Nat Prod Lett. 2001;15(1):27-33.

[2]. Asamenew G, et al. In vitro antimicrobial and antioxidant activities of anthrone and chromone from the latex of Aloe harlana Reynolds. Phytother Res. 2011 Dec;25(12):1756-60.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
789.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C29H30O11

[ Molecular Weight ]:
554.542

[ Flash Point ]:
260.0±26.4 °C

[ Exact Mass ]:
554.178833

[ LogP ]:
3.05

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.653

Related Compounds