Butralin

Names

[ Name ]:
Butralin

[Synonym ]:
AMEX
4-tert-butyl-n-sec-butyl-2,6-dinitroaniline
N-sec-Butyl-4-tert-butyl-2,6-dinitroanilin
Amchem A-280
4-tert-butyl-N-(1-methylpropyl)-2,6-dinitroaniline
Rutralin
Amchem A 280
Zitsaosol
N-(butan-2-yl)-4-tert-butyl-2,6-dinitroaniline
(RS)-N-sec-butyl-4-tert-butyl-2,6-dinitroaniline
N-butan-2-yl-4-tert-butyl-2,6-dinitroaniline
Butalin
N-sec-Butyl-4-(2-methyl-2-propanyl)-2,6-dinitroaniline
4-tert-butyl-2,6-dinitro-N-sec-butylaniline
N-sec-Butyl-4-tert-butyl-2,6-dinitroaniline
4-(1,1-dimethylethyl)-N-(1-methylpropyl)-2,6-dinitrobenzenamine
Butralin
MFCD00128046
Dibutalin
EINECS 251-607-4
rac-N-[(2R)-butan-2-yl]-4-tert-butyl-2,6-dinitroaniline
Amchem 70-25
Amchem-70-25
Butraline
N-(Sec-butyl)-4-(tert-butyl)-2,6-dinitroaniline
Benzenamine, 4-(1,1-dimethylethyl)-N-(1-methylpropyl)-2,6-dinitro-
Tamex

Biological Activity

[Description]:

Butralin is a dinitroaniline herbicide that can be widely used to control single-leaf weeds and some dicotyledons[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Xu X, et al. Gold-based strip sensor for the rapid and sensitive detection of butralin in tomatoes and peppers. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2022 Jul;39(7):1255-1264.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
381.3±42.0 °C at 760 mmHg

[ Melting Point ]:
61ºC

[ Molecular Formula ]:
C₁₄H₂₁N₃O₄

[ Molecular Weight ]:
295.33

[ Flash Point ]:
184.4±27.9 °C

[ Exact Mass ]:
295.153198

[ PSA ]:
103.67000

[ LogP ]:
5.80

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.565

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BW9500000

CHEMICAL NAME :: Aniline, N-sec-butyl-4-tert-butyl-2,6-dinitro-

CAS REGISTRY NUMBER :: 33629-47-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C14-H21-N3-O4

MOLECULAR WEIGHT :: 295.38

WISWESSER LINE NOTATION :: 2Y1&MR BNW FNW DX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SWSPBE Proceedings, Southern Weed Science Society. (Southern Weed Science Society, 309 W. Clark St., Champaign, IL 61820) V.22- 1969- Volume(issue)/page/year: 24,58,1971

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 gm/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SWSPBE Proceedings, Southern Weed Science Society. (Southern Weed Science Society, 309 W. Clark St., Champaign, IL 61820) V.22- 1969- Volume(issue)/page/year: 24,58,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C55,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 12600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 32,125,1978 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Safety Information

[ Symbol ]:

GHS07, GHS08, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319-H341-H410

[ Precautionary Statements ]:
P273-P281-P305 + P351 + P338-P501

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;N: Dangerous for the environment;

[ Risk Phrases ]:
24-36/37/38-50/53

[ Safety Phrases ]:
S26-S36/37-S45-S60-S61

[ RIDADR ]:
1325

[ RTECS ]:
BW9500000

[ Packaging Group ]:
II

[ Hazard Class ]:
4.1

[ HS Code ]:
2921499012

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921499012

[ Summary ]:
2921499012. VAT:17.0%. Tax rebate rate:9.0%. Supervision conditions:S(import or export registration certificate for pesticides). MFN tariff:6.5%. General tariff:30.0%

Articles

Simultaneous residue measurement of pendimethalin, isopropalin, and butralin in tobacco using high-performance liquid chromatography with ultraviolet detection and electrospray ionization/mass spectrometric identification.

J. Agric. Food Chem. 52(23) , 6912-5, (2004)

A simultaneous residue analysis of pendimethalin, isopropalin, and butralin in tobacco was developed with high-performance liquid chromatography with ultraviolet monitoring and electrospray ionization...

[Chemical weed control of medicinal plant Bupleurum falcatum L].

Zhongguo Zhong Yao Za Zhi 25(4) , 210-3, (2000)

To select low-residue herbicide for cultivation of Bupleurum falcatum.Probing the effect of various kinds of herbicide on the budding, growth and yield of B. falcatum both in laboratory and in the fie...

Alpha-tubulin missense mutations correlate with antimicrotubule drug resistance in Eleusine indica.

Plant Cell 10(2) , 297-308, (1998)

Dinitroaniline herbicides are antimicrotubule drugs that bind to tubulins and inhibit polymerization. As a result of repeated application of dinitroaniline herbicides, highly resistant and intermediat...