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2,3,7-Trichlorodibenzo-p-dioxin

Names

[ CAS No. ]:
33857-28-2

[ Name ]:
2,3,7-Trichlorodibenzo-p-dioxin

[Synonym ]:
Dibenzo-p-dioxin,2,3,7-trichloro
2,3,7-trichlorodibenzodioxin

Chemical & Physical Properties

[ Density]:
1.562g/cm3

[ Boiling Point ]:
384.8ºC at 760mmHg

[ Molecular Formula ]:
C12H5Cl3O2

[ Molecular Weight ]:
287.52600

[ Flash Point ]:
152.8ºC

[ Exact Mass ]:
285.93600

[ PSA ]:
18.46000

[ LogP ]:
5.54480

[ Index of Refraction ]:
1.649

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HP3630000
CHEMICAL NAME :
Dibenzo-p-dioxin, 2,3,7-trichloro-
CAS REGISTRY NUMBER :
33857-28-2
BEILSTEIN REFERENCE NO. :
1320418
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C12-H5-Cl3-O2
MOLECULAR WEIGHT :
287.52
WISWESSER LINE NOTATION :
T C666 BO IOJ EG FG LG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3 mg/kg
TOXIC EFFECTS :
Endocrine - changes in spleen weight Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,335,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
29400 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 38,879,1982 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Safety Information

[ HS Code ]:
2932999060

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2932999060

[ Summary ]:
2932999060. Dioxin,Furan(polychorinated dibenzo-p-dioxines,polychlorinated dibenzofurans). VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:89(articles on the list of prohibited export goods,articles on the list of prohibited import goods). MFN tariff:6.5%. General tariff:20.0%


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