Tryptamine-d4 Hydrochloride

Names

[ CAS No. ]:
340257-60-5

[ Name ]:
Tryptamine-d4 Hydrochloride

[Synonym ]:
1,1,2,2-tetradeuterio-2-(1H-indol-3-yl)ethanamine,hydrochloride

Biological Activity

[Description]:

Tryptamine-d4 hydrochloride is the deuterium labeled Tryptamine hydrochloride. Tryptamine hydrochloride, a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Jones RS, et al. Tryptamine: a neuromodulator or neurotransmitter in mammalian brain? Prog Neurobiol. 1982;19(1-2):117-39.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H9D4ClN2

[ Molecular Weight ]:
200.70100

[ Exact Mass ]:
200.10200

[ PSA ]:
41.81000

[ LogP ]:
3.17140

Related Compounds