4-METHYLUMBELLIFERYL-P-GUANIDINOBENZOATE HYDROCHLORIDE

Names

[ Name ]:
4-METHYLUMBELLIFERYL-P-GUANIDINOBENZOATE HYDROCHLORIDE

[Synonym ]:
4-Guanidinobenzoic acid 4-methylumbelliferyl ester hydrochloride,MUGB
(4-methyl-2-oxochromen-7-yl) 4-(diaminomethylideneamino)benzoate,hydrochloride
EINECS 251-871-0

Chemical & Physical Properties

[ Boiling Point ]:
606.3ºC at 760 mmHg

[ Melting Point ]:
219-221ºC

[ Molecular Formula ]:
C₁₈H₁₆ClN₃O₄

[ Molecular Weight ]:
373.79000

[ Flash Point ]:
320.5ºC

[ Exact Mass ]:
373.08300

[ PSA ]:
118.41000

[ LogP ]:
4.30100

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.

Biochem. J. 469 , 243-53, (2015)

Laskowski inhibitors regulate serine proteases by an intriguing mode of action that involves deceiving the protease into synthesizing a peptide bond. Studies exploring naturally occurring Laskowski in...

Some sensitive methods for the assay of trypsinlike enzymes.

Meth. Enzymol. 45 , 12, (1976)

Determination of the operational molarity of solutions of bovine alpha-chymotrypsin, trypsin, thrombin and factor Xa by spectrofluorimetric titration.

Biochem. J. 131 , 107, (1973)

Several esters of 4-methylumbelliferone and 2-naphthol were synthesized and examined as possible spectrofluorimetric titrants for bovine alpha-chymotrypsin, trypsin, thrombin, Factor Xa and for subtil...