Orexin A (17-33) trifluoroacetate salt

Names

[ Name ]:
Orexin A (17-33) trifluoroacetate salt

Biological Activity

[Description]:

OXA(17-33) is a potent and selective orexin-1 receptor (OX1) agonist. OXA(17-33) shows a ∼23-fold selectivity for the OX1 (EC50=8.29 nM) over OX2 (187 nM)[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Orexin Receptor (OX Receptor)

Research Areas >> Neurological Disease

[Target]

OX1:8.29 nM (EC50)

OX2:187 nM (EC50)

[References]

[1]. German NA, et al. Truncated Orexin Peptides: Structure-Activity Relationship Studies. ACS Med Chem Lett. 2013;4(12):1224-1227.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₉H₁₂₅N₂₃O₂₂

[ Molecular Weight ]:
1748.98

Orexin A (17-33) trifluoroacetate salt

Names

Biological Activity

Chemical & Physical Properties

Related Compounds