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Sydnophene

Names

[ CAS No. ]:
3441-64-3

[ Name ]:
Sydnophene

[Synonym ]:
5-amino-3-(1-phenylpropan-2-yl)-2,3-dihydro-1,2,3-oxadiazol-2-ium chloride
sydnophen monohydrochloride
Sydnophen hydrochloride
Sydnone imine,3-(1-methyl-2-phenylethyl)-,monohydrochloride
Sydnophene
3-phenylisopropylsydnonimine
Sydnophene hydrochloride
Sidnofen

Chemical & Physical Properties

[ Molecular Formula ]:
C11H16ClN3O

[ Molecular Weight ]:
241.71700

[ Exact Mass ]:
241.09800

[ PSA ]:
55.10000

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WU7682000
CHEMICAL NAME :
Sydnone imine, 3-(alpha-methylphenethyl)-, monohydrochloride
CAS REGISTRY NUMBER :
3441-64-3
LAST UPDATED :
199403
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C11-H13-N3-O.Cl-H
MOLECULAR WEIGHT :
239.73

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
225 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 35,169,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
123 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 35,169,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
51 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 35,169,1972

Safety Information

[ Risk Phrases ]:
20/21/22

[ RIDADR ]:
UN 2811 6.1/PG 2

[ HS Code ]:
2934999090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds