Centpropazine

Names

[ CAS No. ]:
34675-77-9

[ Name ]:
Centpropazine

[Synonym ]:
Centpropazine
Centropazine

Chemical & Physical Properties

[ Density]:
1.147g/cm3

[ Boiling Point ]:
560.7ºC at 760mmHg

[ Molecular Formula ]:
C₂₂H₂₈N₂O₃

[ Molecular Weight ]:
368.46900

[ Flash Point ]:
292.9ºC

[ Exact Mass ]:
368.21000

[ PSA ]:
53.01000

[ LogP ]:
2.84410

[ Index of Refraction ]:
1.576

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UC2984000

CHEMICAL NAME :: 1-Propanone, 1-(4-(2-hydroxy-3-(4-phenyl-1-piperazinyl)propoxy)phe nyl)-

CAS REGISTRY NUMBER :: 34675-77-9

BEILSTEIN REFERENCE NO. :: 0578135

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C22-H28-N2-O3

MOLECULAR WEIGHT :: 368.52

WISWESSER LINE NOTATION :: T6N DNTJ A1YQ1OR DV2& DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 1710 ug/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 5,338,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 270 mg/kg

TOXIC EFFECTS :: Behavioral - wakefulness

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,286,1972

Safety Information

[ HS Code ]:
2933599090

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%