3,6-Dichloro-2-[(2H3)methyloxy]benzoic acid

Names

[ Name ]:
3,6-Dichloro-2-[(2H3)methyloxy]benzoic acid

[Synonym ]:
3,6-Dichloro-2-methoxy-d3-benzoic Acid
3,6-Dichloro-2-[(H)methyloxy]benzoic acid
Dianat-d3
Dicamba-d3
Benzoic acid, 3,6-dichloro-2-(methyl-d-oxy)-
Velsicol 58-CS-11-d3
Banvel-d3
Clarity-d3

Biological Activity

[Description]:

Dicamba-d3 is the deuterium labeled Methyl (3,4-dichlorophenyl)carbamate[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
326.1±37.0 °C at 760 mmHg

[ Melting Point ]:
114-116ºC

[ Molecular Formula ]:
C₈H₃D₃Cl₂O₃

[ Molecular Weight ]:
224.06

[ Flash Point ]:
151.0±26.5 °C

[ Exact Mass ]:
222.988235

[ PSA ]:
46.53000

[ LogP ]:
2.76

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.577

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318-H412

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-41-52/53

[ Safety Phrases ]:
26-61

[ RIDADR ]:
UN 3077 9/PG 3