L-Valine-d8

Names

[ Name ]:
L-Valine-d8

[Synonym ]:
Valine-2,3,4,4,4,4',4',4'-d
(2,3,4,4,4,4',4',4'-H)Valine
L-Valine-d8
D8-L-valine
MFCD00144704
L-|A-Amino-|A-methylbutyric Acid-d8

Biological Activity

[Description]:

L-Valine-d8 (L-VALINE-2,3,4,4,4,5,5,5-D8) is a stable-isotope label reagent, is use in the labelled synthesis of L-valineamide-d8 intermediate[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. [1] Iyer MR, et al. Synthesis of S-2-((S)-3-(4-chlorophenyl)-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-(methyl-d₃)butanamide-d₅, octadeuterated JD5037. J Labelled Comp Radiopharm. 2017;60(10):460-465.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
213.6±23.0 °C at 760 mmHg

[ Melting Point ]:
295-300 â„ƒ (subl. )(lit.)

[ Molecular Formula ]:
C₅H₃D₈NO₂

[ Molecular Weight ]:
125.20

[ Flash Point ]:
83.0±22.6 °C

[ Exact Mass ]:
125.129196

[ PSA ]:
63.32000

[ LogP ]:
0.20

[ Vapour Pressure ]:
0.1±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.461

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

Articles

Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy.

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Defects in mitochondrial fusion or fission are associated with many pathologies, raising the hope that pharmacological manipulation of mitochondrial dynamics may have therapeutic benefit. This approac...