Hydroxy ipronidazole

Names

[ Name ]:
Hydroxy ipronidazole

[Synonym ]:
IPZOH
Hydroxyipronidazole
2-(1-Methyl-5-nitro-1H-imidazol-2-yl)propan-2-ol Hydroxy-ipronidazole IPZOH
Ipronidazole-OH

Biological Activity

[Description]:

Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kamila Mitrowska, et al. Transfer of nitroimidazoles from contaminated beeswax to honey. Food Addit Contam Part A Chem Anal Control Expo Risk Assess.2017 Apr;34(4):573-581.

Chemical & Physical Properties

[ Density]:
1.34 g/cm3

[ Boiling Point ]:
367.7ºC at 760 mmHg

[ Melting Point ]:
108-110°C

[ Molecular Formula ]:
C₇H₁₁N₃O₃

[ Molecular Weight ]:
185.18100

[ Flash Point ]:
176.2ºC

[ Exact Mass ]:
185.08000

[ PSA ]:
83.87000

[ LogP ]:
1.07890

[ Index of Refraction ]:
1.579

[ Storage condition ]:
-20?C Freezer

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933290090

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Simultaneous determination of 15 nitroimidazoles in cosmetics by HPLC coupled with electrospray ionization- tandem mass spectrometry.

J. AOAC Int. 97(6) , 1538-45, (2015)

A sensitive and reliable analytical method based on HPLC/MSIMS has been developed for the simultaneous determination of 15 nitroimidazoles in cosmetics. A diversity of cosmetic samples, including powd...