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Emeramide

Names

[ CAS No. ]:
351994-94-0

[ Name ]:
Emeramide

[Synonym ]:
UNII-4U7K5X4ANS
N,N’-Bis(2-mercaptoethyl)-1,3-isophthalamide
N,N′-bis(2-mercaptoethyl)isophthalamide
BDETH2
1,3-Benzenedicarboxamide, N,N-bis(2-mercaptoethyl)-
MetX
N,N′-Bis(2-mercaptoethyl)-1,3-benzenedicarboxamide
N,N'-Bis(2-sulfanylethyl)isophthalamide
BDET
BDTH2
benzene-1,3-diamidoethanethiol

Biological Activity

[Description]:

Emeramide is a novel lipid-soluble, thiol-redox antioxidant and heavy metal chelator.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cancer
Research Areas >> Inflammation/Immunology

[References]

[1]. Secor JD, et al. Novel lipid-soluble thiol-redox antioxidant and heavy metal chelator, N,N'-bis(2-mercaptoethyl)isophthalamide (NBMI) and phospholipase D-specific inhibitor, 5-fluoro-2-indolyl des-chlorohalopemide (FIPI) attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. Int J Toxicol. 2011 Dec;30(6):619-38.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
568.9±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H16N2O2S2

[ Molecular Weight ]:
284.398

[ Flash Point ]:
297.9±28.7 °C

[ Exact Mass ]:
284.065308

[ PSA ]:
142.78000

[ LogP ]:
1.16

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.595

[ Storage condition ]:
2-8℃

Related Compounds