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(Z)-Desbutyl Lumefantrine

Names

[ CAS No. ]:
355841-11-1

[ Name ]:
(Z)-Desbutyl Lumefantrine

[Synonym ]:
9H-Fluorene-4-methanol, α-[(butylamino)methyl]-2,7-dichloro-9-[(4-chlorophenyl)methylene]-, (9Z)-
UNII:07L7O84HGW
2-(Butylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol

Biological Activity

[Description]:

Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[References]

[1]. Wong RP, et al. Desbutyl-lumefantrine is a metabolite of lumefantrine with potent in vitro antimalarial activity that may influence artemether-lumefantrine treatment outcome. Antimicrob Agents Chemother. 2011 Mar;55(3):1194-8.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
626.8±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H24Cl3NO

[ Molecular Weight ]:
472.834

[ Flash Point ]:
332.9±31.5 °C

[ Exact Mass ]:
471.092346

[ PSA ]:
32.26000

[ LogP ]:
9.09

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.661

Related Compounds