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Zylofuramine

Names

[ CAS No. ]:
3563-92-6

[ Name ]:
Zylofuramine

Biological Activity

[Description]:

Zylofuramine is a psychomotor stimulant[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. HARRIS LS, et al. ALPHA-BENZYLTETRAHYDROFURFURYLAMINES--A NEW SERIES OF PSYCHOMOTOR STIMULANTS. III. THE PHARMACOLOGY OF D-THREO ALPHA-BENZYL-N-ETHYLTETRAHYDROFURFURYLAMINE (ZYLOFURAMINE). Arch Int Pharmacodyn Ther. 1963 Dec 1;146:392-405.

Chemical & Physical Properties

[ Density]:
1.006g/cm3

[ Boiling Point ]:
328.8ºC at 760mmHg

[ Molecular Formula ]:
C14H21NO

[ Molecular Weight ]:
219.32300

[ Flash Point ]:
137.2ºC

[ Exact Mass ]:
219.16200

[ PSA ]:
21.26000

[ LogP ]:
2.77710

[ Index of Refraction ]:
1.523

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LU9400000
CHEMICAL NAME :
Furfurylamine, alpha-benzyl-N-ethyl-tetrahydro-, D-threo-
CAS REGISTRY NUMBER :
3563-92-6
BEILSTEIN REFERENCE NO. :
1371229
LAST UPDATED :
199712
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C14-H21-N-O
MOLECULAR WEIGHT :
219.36
WISWESSER LINE NOTATION :
T5OTJ BYM2&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
475 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 146,392,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
155 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 146,392,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
32 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 146,392,1963

Related Compounds