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(β,β-2H2)Tyrosine

Names

[ CAS No. ]:
35693-18-6

[ Name ]:
(β,β-2H2)Tyrosine

[Synonym ]:
(β,β-H)Tyrosine
Tyrosine-β,β-d

Biological Activity

[Description]:

DL-Tyrosine-d2 is the deuterium labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine)[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. ClementeBretti, et al. Some thermodynamic properties of dl-Tyrosine and dl-Tryptophan. Effect of the ionic medium, ionic strength and temperature on the solubility and acid–base properties. Fluid Phase Equilibria.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
385.2±32.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H9D2NO3

[ Molecular Weight ]:
183.20

[ Flash Point ]:
186.7±25.1 °C

[ Exact Mass ]:
183.086441

[ PSA ]:
83.55000

[ LogP ]:
0.38

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.614

[ Storage condition ]:
-20C


Related Compounds