Moslosooflavone

Names

[ Name ]:
Moslosooflavone

[Synonym ]:
7-O-methylwogonin
4H-1-Benzopyran-4-one, 5-hydroxy-7,8-dimethoxy-2-phenyl-
Ambotz
5-Hydroxy-7,8-dimethoxy-2-phenyl-4H-chromen-4-one
5-hydroxy-7,8-dimethoxy-2-phenyl-chromen-4-one
5-hydroxy-7,8-dimehtoxyflavone
norwogenin-6,7-dimethyl ether
7-O-methylwogonine
Moslosooflavone
5-Hydroxy-7,8-dimethoxyflavone

Biological Activity

[Description]:

Moslosooflavone is a flavonoid isolated from Saussurea involucrata. Moslosooflavone has an anti-hypoxia and anti-inflammatory activities[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[In Vitro]

Moslosooflavone can significantly inhibits the transcriptional activity of NF-kappaB in LPS/IFN-gamma stimulated RAW 264.7 macrophages[2].

[References]

[1]. Jing LL, et al. Chemical Constituents with Anti-hypoxia Activity from Saussurea involucrata. Zhong Yao Cai. 2015 Jan;38(1):89-92.

[2]. Chao WW, et al.Anti-inflammatory activity of new compounds from Andrographis paniculata by NF-kappaB transactivation inhibition.J Agric Food Chem. 2010 Feb 24;58(4):2505-12.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
532.9±50.0 °C at 760 mmHg

[ Melting Point ]:
182-183℃

[ Molecular Formula ]:
C₁₇H₁₄O₅

[ Molecular Weight ]:
298.290

[ Flash Point ]:
200.6±23.6 °C

[ Exact Mass ]:
298.084137

[ PSA ]:
68.90000

[ LogP ]:
2.52

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.622

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2914509090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

[Studies on Mosla soochowensis Matsuda. II. Isolation and structure of moslosooflavone (author's transl)].

Yao Xue Xue Bao 17(2) , 151-3, (1982)

[Studies on the chemical constituents in herb of Ranunculus japonicus].

Zhongguo Zhong Yao Za Zhi 31(11) , 892-4, (2006)

To isolate and determine the chemical constituents from Ranunculus japonicus.Compounds were isolated by column chromatography, and identified by MS, NMR data.Nine compounds were obtained andelucidated...

[Chemical constituents from Elsholtzia blanda].

Zhongguo Zhong Yao Za Zhi 30(20) , 1589-91, (2005)

To investigate the constituents of Elsholtzia blanda.The chemical components were isolated by polyamide and silica gel column chromatography. Their structures were identified with extensive spectral (...