15(S)-15-methyl Prostaglandin E2

Names

[ Name ]:
15(S)-15-methyl Prostaglandin E2

[Synonym ]:
9-OXO-11ALPHA,15S-DIHYDROXY-15-METHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID
(5Z,11α,13E,15S)-11,15-Dihydroxy-15-methyl-9-oxoprosta-5,13-dien-1-oic acid
,15s,17z)
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-15-methyl-9-oxo-, (5Z,11α,13E,15S)-

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
535.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₃₄O₅

[ Molecular Weight ]:
366.492

[ Flash Point ]:
291.7±26.6 °C

[ Exact Mass ]:
366.240631

[ PSA ]:
94.83000

[ LogP ]:
2.23

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.557

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UK7896000

CHEMICAL NAME :: Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-15-methyl-9-oxo-, (5Z,11-alpha,13E,15S,17Z)-

CAS REGISTRY NUMBER :: 35700-27-7

LAST UPDATED :: 198910

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C21-H34-O5

MOLECULAR WEIGHT :: 366.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 500 ng/kg

SEX/DURATION :: female 13 week(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - abortion

REFERENCE :: JOGBAS Journal of Obstetrics and Gynaecology of the British Commonwealth. (London, UK) V.68-81, 1961-74. For publisher information, see BJOGAS. Volume(issue)/page/year: 79,737,1972

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraplacental

DOSE :: 1 ug/kg

SEX/DURATION :: female 15 week(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - abortion

REFERENCE :: JOGBAS Journal of Obstetrics and Gynaecology of the British Commonwealth. (London, UK) V.68-81, 1961-74. For publisher information, see BJOGAS. Volume(issue)/page/year: 79,737,1972

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravaginal

DOSE :: 1 ug/kg

SEX/DURATION :: female 14 week(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - abortion

REFERENCE :: JOGBAS Journal of Obstetrics and Gynaecology of the British Commonwealth. (London, UK) V.68-81, 1961-74. For publisher information, see BJOGAS. Volume(issue)/page/year: 79,737,1972